A woman (Elizabeth Perkins) develops a bond with her mentally ill sister (Kathy Bates).
Christine Chapman (Kathy Bates) suffers from schizophrenia, and is unable to live without the assistance of her mother, Helen (Lynn Redgrave). Christine's younger sister, Judy (Elizabeth Perkins), has avoided taking care of Christine growing up and is now living in a different city. But when their mother dies, Judy suddenly finds that she is Christine's caretaker. The self-centered Judy is now forced to reevaluate her priorities, while Christine continues her own quest for independence.