Description
Original Airdate06/10/2026
Following people from around the globe living with rare and remarkable physical conditions.
Most Extreme Humans
Where to watch Most Extreme Humans
- Free On Demand on TLC
Season 1
10. Bending the Rules
Air Date 08/12/2026
In Indonesia, Dimas dreams of becoming a martial arts warrior, but his family worries the training will harm his oddly bendy body; in Colombia, Herson's backward-bending knees are failing, and he questions his dream of proposing to his girlfriend.
9. On My Side
Air Date 08/05/2026
Ecuadorian conjoined twins Jose Luis and Jose Armando leave their home and family to get advanced medical care for a chance at independence; teenaged Thai conjoined twins Pin and Panmustnavigate their ongoing differencesas they prepare for adulthood.
7. Skin in the Game
Air Date 07/22/2026
Mahfuza and Nelly are living with Harlequin ichthyosis, one of the world's rarest and most severe skin conditions; Mahfuza prepares for her first boxing match; Nelly fully supports her friend but worries that the high risks may outweigh the rewards.
6. Hair Today, Gone Tomorrow?
Air Date 07/15/2026
In rural Indian, Lalit's face and body have been thickly covered in hair since the day he was born; doctors theorized that the hair would fall out once he reached peak maturity; now that he's turning 20, Lalit seeks out a specialist to learn his fate.
5. Face to Face
Air Date 07/08/2026
Milagros lives with tumors so heavy that her face droops down to her torso; after hiding away, a health scare is forcing her out into the world; twenty-one-year-old Lizzie is preparing to live independently even after tumors have grown over her eyes.
4. Peaks and Valleys
Air Date 07/01/2026
Life defined by height: in Turkey, the world's tallest woman lives with an unknown genetic condition linked to extreme growth and fragile bones, while in Brazil, the world's shortest couple navigate dwarfism and its physical challenges.
3. Upside Down With a Twist
Air Date 06/24/2026
In Brazil, Claudio lives with a condition that bent his head backward; ahead of his 50th birthday, he wants to climb a sacred mountain; in Norway, Birgitte lives with a different presentation of the same condition; she's training for the next Paralympics.
2. Ugliest Man
Air Date 06/17/2026
Winner of the Uganda's Ugliest Man contest, Godfrey has a rare disorder that has left him disfigured; with 10 children, a new baby on the way, and his condition worsening, he is seeking medical answers that will determine his future.
1. Biggest Hands
Air Date 06/10/2026
Mark's hands are 20 times bigger than a normal adult male's; after learning that his condition may require amputation, Mark stopped seeing doctors; now troubling changes to his hands mean he must go back. If not for himself, then for his young daughter.