Drs. Terry Dubrow and Paul Nassif leave their Southern California home base to try to help patients across America who have been botched by genetics or traumatic incidents. The doctors travel the country in search of people who are willing to share their stories on TV and in return have their lives transformed by the physicians. As they spend time together on the road, Dubrow and Nassif learn things about each other that they never thought they'd know. The hourlong episodes also see the doctors checking in with former patients from "Botched."